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Critical Glycosylated Residues in Exon Three of Erythrocyte Glycophorin A Engage Plasmodium falciparum EBA-175 and Define Receptor Specificity

Erythrocyte invasion is an essential step in the pathogenesis of malaria. The erythrocyte binding-like (EBL) family of Plasmodium falciparum proteins recognizes glycophorins (Gp) on erythrocytes and plays a critical role in attachment during invasion. However, the molecular basis for specific recept...

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Bibliografske podrobnosti
Main Authors: Salinas, Nichole D., Paing, May M., Tolia, Niraj H.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173783/
https://ncbi.nlm.nih.gov/pubmed/25205096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01606-14
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