Co-delivery of Doxorubicin and Bmi1 siRNA by Folate Receptor Targeted Liposomes Exhibits Enhanced Anti-Tumor Effects in vitro and in vivo

Bmi1 gene overexpression is found in various human tumors and has been shown as a potential target for gene treatment. However, siRNA-based treatments targeting Bmi1 gene have been restricted to limited delivery, low bioavailability and hence relatively reduced efficacy. To overcome these barriers,...

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Hlavní autoři: Yang, Tan, Li, Bin, Qi, Shibo, Liu, Yong, Gai, Yongkang, Ye, Peng, Yang, Guang, Zhang, Wendian, Zhang, Peng, He, Xingxing, Li, Weijie, Zhang, Zhiping, Xiang, Guangya, Xu, Chuanrui
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173760/
https://ncbi.nlm.nih.gov/pubmed/25285163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.9423
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