Co-delivery of Bmi1 small interfering RNA with ursolic acid by folate receptor-targeted cationic liposomes enhances anti-tumor activity of ursolic acid in vitro and in vivo

Overexpression of Bmi1 gene is an important feature of cancer stem cell in various human tumors. Therefore, Bmi1 gene can be a potential target for small interfering RNA (siRNA) mediated cancer therapy. Ursolic acid (UA) as a natural product plays a pivotal role in anti-tumor field, although its per...

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Bibliografiske detaljer
Udgivet i:Drug Deliv
Main Authors: Li, Weijie, Yan, Ruicong, Liu, Yong, He, Chuanchuan, Zhang, Xiaojuan, Lu, Yao, Khan, Muhammad Waseem, Xu, Chuanrui, Yang, Tan, Xiang, Guangya
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711155/
https://ncbi.nlm.nih.gov/pubmed/31366257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1645244
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