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Patched Targeting Peptides for Imaging and Treatment of Hedgehog Positive Breast Tumors

High tumor hedgehog expression is correlated with poor prognosis in invasive ductal carcinoma. Peptides which bind the patched receptor have recently been reported to have a growth inhibitory effect in tumors with activated hedgehog signaling. We sought to examine growth inhibition with these peptid...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Smith, Daniel, Kong, Fanlin, Yang, David, Larson, Richard, Sims-Mourtada, Jennifer, Woodward, Wendy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172929/
https://ncbi.nlm.nih.gov/pubmed/25276795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/525680
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