Patched Targeting Peptides for Imaging and Treatment of Hedgehog Positive Breast Tumors

High tumor hedgehog expression is correlated with poor prognosis in invasive ductal carcinoma. Peptides which bind the patched receptor have recently been reported to have a growth inhibitory effect in tumors with activated hedgehog signaling. We sought to examine growth inhibition with these peptid...

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Hlavní autoři: Smith, Daniel, Kong, Fanlin, Yang, David, Larson, Richard, Sims-Mourtada, Jennifer, Woodward, Wendy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172929/
https://ncbi.nlm.nih.gov/pubmed/25276795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/525680
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