Microglia display modest phagocytic capacity for extracellular tau oligomers

BACKGROUND: Abnormal misfolded tau protein is a driving force of neurofibrillary degeneration in Alzheimer’s disease. It has been shown that tau oligomers play a crucial role in the formation of intracellular neurofibrillary tangles. They are intermediates between soluble tau monomers and insoluble...

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Détails bibliographiques
Auteurs principaux: Majerova, Petra, Zilkova, Monika, Kazmerova, Zuzana, Kovac, Andrej, Paholikova, Kristina, Kovacech, Branislav, Zilka, Norbert, Novak, Michal
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172893/
https://ncbi.nlm.nih.gov/pubmed/25217135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0161-z
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