TR-FRET-Based High-Throughput Screening Assay for Identification of UBC13 Inhibitors

UBC13 is a non-canonical Ubiquitin Conjugating Enzyme (E2) that has been implicated in a variety of cellular signaling processes due to its ability to catalyze formation of Lysine 63-linked polyubiquitin chains on various substrates. In particular, UBC13 is required for signaling by a variety of rec...

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Detaylı Bibliyografya
Asıl Yazarlar: Madiraju, Charitha, Welsh, Kate, Cuddy, Michael P., Godoi, Paulo, Pass, Ian, Ngo, Tram, Vasile, Stefan, Sergienko, Eduard A., Diaz, Paul, Matsuzawa, Shu-Ichi, Reed, John C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172584/
https://ncbi.nlm.nih.gov/pubmed/22034497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057111423417
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