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TDP-43 is a key player in the clinical features associated with Alzheimer’s disease

The aim of this study was to determine whether the TAR DNA-binding protein of 43kDa (TDP-43) independently has any effect on the clinical and neuroimaging features typically ascribed to Alzheimer’s disease (AD) pathology, and whether TDP-43 pathology could help shed light on the phenomenon of resili...

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Hlavní autoři: Josephs, Keith A., Whitwell, Jennifer L., Weigand, Stephen D., Murray, Melissa E., Tosakulwong, Nirubol, Liesinger, Amanda M., Petrucelli, Leonard, Senjem, Matthew L., Knopman, David S., Boeve, Bradley F., Ivnik, Robert J., Smith, Glenn E., Jack, Clifford R., Parisi, Joseph E., Petersen, Ronald C., Dickson, Dennis W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172544/
https://ncbi.nlm.nih.gov/pubmed/24659241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1269-z
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