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TDP-43 and pathological subtype of Alzheimer’s disease impact clinical features

OBJECTIVE: To determine whether the frequency of TDP-43 deposition in Alzheimer’s disease (AD) differs across pathologically defined AD subtypes (Hippocampal sparing [HpSp]; Typical and Limbic), and to further examine the relationship between TDP-43, pathological subtype, and clinical features in AD...

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Vydáno v:Ann Neurol
Hlavní autoři: Josephs, Keith A., Whitwell, Jennifer L., Tosakulwong, Nirubol, Weigand, Stephen D., Murray, Melissa E., Serie, Amanda M., Petrucelli, Leonard, Senjem, Matthew L., Ivnik, Robert J., Parisi, Joseph E., Petersen, Ronald C., Dickson, Dennis W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623932/
https://ncbi.nlm.nih.gov/pubmed/26224156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24493
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