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TDP-43 and pathological subtype of Alzheimer’s disease impact clinical features

OBJECTIVE: To determine whether the frequency of TDP-43 deposition in Alzheimer’s disease (AD) differs across pathologically defined AD subtypes (Hippocampal sparing [HpSp]; Typical and Limbic), and to further examine the relationship between TDP-43, pathological subtype, and clinical features in AD...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Josephs, Keith A., Whitwell, Jennifer L., Tosakulwong, Nirubol, Weigand, Stephen D., Murray, Melissa E., Serie, Amanda M., Petrucelli, Leonard, Senjem, Matthew L., Ivnik, Robert J., Parisi, Joseph E., Petersen, Ronald C., Dickson, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623932/
https://ncbi.nlm.nih.gov/pubmed/26224156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24493
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