Deleted in Breast Cancer 1 regulates cellular senescence during obesity

Chronic obesity leads to inflammation, tissue dysfunction, and cellular senescence. It was proposed that cellular senescence during obesity and aging drives inflammation and dysfunction. Consistent with this, clearance of senescent cells increases healthspan in progeroid mice. Here, we show that the...

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Detalhes bibliográficos
Main Authors: Escande, Carlos, Nin, Veronica, Pirtskhalava, Tamar, Chini, Claudia C, Thereza Barbosa, Maria, Mathison, Angela, Urrutia, Raul, Tchkonia, Tamar, Kirkland, James L, Chini, Eduardo N
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Short Takes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172532/
https://ncbi.nlm.nih.gov/pubmed/24992635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12235
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