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A genomics approach identifies senescence-specific gene expression regulation
Replicative senescence is a fundamental tumor-suppressive mechanism triggered by telomere erosion that results in a permanent cell cycle arrest. To understand the impact of telomere shortening on gene expression, we analyzed the transcriptome of diploid human fibroblasts as they progressed toward an...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172521/ https://ncbi.nlm.nih.gov/pubmed/24863242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12234 |
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