Inhibition of BET Bromodomain Targets Genetically Diverse Glioblastoma

PURPOSE: Glioblastoma is refractory to conventional therapies. The bromodomain and extraterminal domain (BET) proteins are epigenetic readers that selectively bind to acetylated lysine residues on histone tails. These proteins recently emerged as important therapeutic targets in NUT midline carcinom...

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Detaylı Bibliyografya
Asıl Yazarlar: Cheng, Zhixiang, Gong, Yuanying, Ma, Yufang, Lu, Kaihua, Lu, Xiang, Pierce, Larry A., Thompson, Reid C., Muller, Susanne, Knapp, Stefan, Wang, Jialiang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172367/
https://ncbi.nlm.nih.gov/pubmed/23403638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3066
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