Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients

Spinal and bulbar muscular atrophy (SBMA, Kennedy’s disease), is a motor neuron disease caused by polyglutamine repeat expansion in the androgen receptor. Although degeneration occurs in the spinal cord and muscle, the exact mechanism is not clear. Induced pluripotent stem cells from spinal and bulb...

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Detalhes bibliográficos
Main Authors: Grunseich, Christopher, Zukosky, Kristen, Kats, Ilona R., Ghosh, Laboni, Harmison, George G., Bott, Laura C., Rinaldi, Carlo, Chen, Ke-lian, Chen, Guibin, Boehm, Manfred, Fischbeck, Kenneth H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172362/
https://ncbi.nlm.nih.gov/pubmed/24925468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.05.038
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