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Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients
Spinal and bulbar muscular atrophy (SBMA, Kennedy’s disease), is a motor neuron disease caused by polyglutamine repeat expansion in the androgen receptor. Although degeneration occurs in the spinal cord and muscle, the exact mechanism is not clear. Induced pluripotent stem cells from spinal and bulb...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172362/ https://ncbi.nlm.nih.gov/pubmed/24925468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.05.038 |
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