Systemic Administration of the Antioxidant/Iron Chelator α-Lipoic Acid Protects Against Light-Induced Photoreceptor Degeneration in the Mouse Retina

PURPOSE. Oxidative stress and inflammation have key roles in the light damage (LD) model of retinal degeneration as well as in age-related macular degeneration (AMD). We sought to determine if lipoic acid (LA), an antioxidant and iron chelator, protects the retina against LD. METHODS. Balb/c mice we...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhao, Liangliang, Wang, Chenguang, Song, Delu, Li, Yafeng, Song, Ying, Su, Guanfang, Dunaief, Joshua L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Association for Research in Vision and Ophthalmology 2014
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172298/
https://ncbi.nlm.nih.gov/pubmed/25146987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15025
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