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WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc–dependent manner
Hematopoiesis is fully dependent on hematopoietic stem cells (HSCs) that possess the capacity to self-renew and differentiate into all blood cell lineages. WASH, Wiskott–Aldrich syndrome protein (WASP) and SCAR homologue (WASH) is involved in endosomal sorting as an actin-nucleating protein. Here, w...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172220/ https://ncbi.nlm.nih.gov/pubmed/25225459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140169 |
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