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Glutamylation of deubiquitinase BAP1 controls self-renewal of hematopoietic stem cells and hematopoiesis

All hematopoietic lineages are derived from a limited pool of hematopoietic stem cells (HSCs). Although the mechanisms underlying HSC self-renewal have been extensively studied, little is known about the role of protein glutamylation and deglutamylation in hematopoiesis. Here, we show that carboxype...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Xiong, Zhen, Xia, Pengyan, Zhu, Xiaoxiao, Geng, Jingjing, Wang, Shuo, Ye, Buqing, Qin, Xiwen, Qu, Yuan, He, Luyun, Fan, Dongdong, Du, Ying, Tian, Yong, Fan, Zusen
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041701/
https://ncbi.nlm.nih.gov/pubmed/31699823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190974
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