NLRP7 inter-domain interactions: the NACHT-associated domain is the physical mediator for oligomeric assembly

Mutations in NLRP7 (NOD-like-receptor family, pyrin domain containing 7) are responsible for a type of recurrent pregnancy loss known as recurrent hydatidiform mole (HYDM1). This condition is characterized by abnormal growth of the placenta, a lack of proper embryonic development and abnormal methyl...

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Detalhes bibliográficos
Main Authors: Singer, Heike, Biswas, Arijit, Zimmer, Nicole, Messaed, Christiane, Oldenburg, Johannes, Slim, Rima, El-Maarri, Osman
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172174/
https://ncbi.nlm.nih.gov/pubmed/25082979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gau060
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