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Determining inter-domain structure and dynamics of a retroviral capsid protein in the presence of oligomerization: implication for structural transition in capsid assembly
Capsid (CA) proteins from all retroviruses, including HIV-1, are structurally homologous dual-domain helical proteins. They form a capsid lattice composed of unitary symmetric CA hexamers. X-ray crystallography has shown that within each hexamer a monomeric CA adopts a single conformation where most...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020516/ https://ncbi.nlm.nih.gov/pubmed/23906107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400592d |
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