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Expansion of biological pathways based on evolutionary inference

Availability of diverse genomes makes it possible to predict gene function based on shared evolutionary history. This approach can be challenging, however, for pathways whose components do not exhibit a shared history, but rather, consist of distinct “evolutionary modules.” We introduce a computatio...

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Détails bibliographiques
Auteurs principaux: Li, Yang, Calvo, Sarah E., Gutman, Roee, Liu, Jun S., Mootha, Vamsi K.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171950/
https://ncbi.nlm.nih.gov/pubmed/24995987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.034
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