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Expansion of biological pathways based on evolutionary inference

Availability of diverse genomes makes it possible to predict gene function based on shared evolutionary history. This approach can be challenging, however, for pathways whose components do not exhibit a shared history, but rather, consist of distinct “evolutionary modules.” We introduce a computatio...

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Detalles Bibliográficos
Main Authors: Li, Yang, Calvo, Sarah E., Gutman, Roee, Liu, Jun S., Mootha, Vamsi K.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171950/
https://ncbi.nlm.nih.gov/pubmed/24995987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.034
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