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Pharmacokinetics of dexmedetomidine combined with therapeutic hypothermia in a piglet asphyxia model
BACKGROUND: The highly selective α(2)-adrenoreceptor agonist, dexmedetomidine, exerts neuroprotective, analgesic, anti-inflammatory and sympatholytic properties that may be beneficial for perinatal asphyxia. The optimal safe dose for pre-clinical newborn neuroprotection studies is unknown. METHODS:...
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| Autori principali: | , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Publishing Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4171780/ https://ncbi.nlm.nih.gov/pubmed/24724965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aas.12318 |
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