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Deletion of a Single β-catenin Allele in Osteocytes Abolishes the Bone Anabolic Response to Loading

The Wnt/β-catenin signaling pathway is essential for bone cell viability, function and for skeletal integrity. To determine if β-catenin in osteocytes plays a role in the bone anabolic response to mechanical loading, 18-24 wk old osteocyte β-catenin haploinsufficient mice (Dmp1-Cre x β-catenin fl/+;...

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Bibliografske podrobnosti
Main Authors: Javaheri, B., Stern, A., Lara, N., Dallas, M., Zhao, H, Liu, Y, Bonewald, L.F., Johnson, M.L.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171742/
https://ncbi.nlm.nih.gov/pubmed/23929793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2064
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