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Deletion of a Single β-catenin Allele in Osteocytes Abolishes the Bone Anabolic Response to Loading
The Wnt/β-catenin signaling pathway is essential for bone cell viability, function and for skeletal integrity. To determine if β-catenin in osteocytes plays a role in the bone anabolic response to mechanical loading, 18-24 wk old osteocyte β-catenin haploinsufficient mice (Dmp1-Cre x β-catenin fl/+;...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4171742/ https://ncbi.nlm.nih.gov/pubmed/23929793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2064 |
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