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In Vivo Mechanical Loading Rapidly Activates β–catenin Signaling in Osteocytes through a Prostaglandin Mediated Mechanism

The response of the skeleton to loading appears to be mediated through the activation of the Wnt/β-catenin signaling pathway and osteocytes have long been postulated to be the primary mechanosensory cells in bone. To examine the kinetics of the mechanoresponse of bone and cell types involved in the...

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Bibliografiska uppgifter
I publikationen:Bone
Huvudupphovsmän: Lara-Castillo, N, Kim-Weroha, NA, Kamel, MA, Javaheri, B, Ellies, DL, Krumlauf, RE, Thiagarajan, G, Johnson, ML
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447591/
https://ncbi.nlm.nih.gov/pubmed/25836764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.03.019
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