The stress-response sensor Chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors

Adaptation of malignant cells to the hostile milieu present in tumors is an important determinant for their survival and growth. However, the interaction between tumor-linked stress and anti-tumor immunity remains poorly characterized. Here, we show the critical role of the cellular stress sensor C/...

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Main Authors: Thevenot, Paul T., Sierra, Rosa A., Raber, Patrick L., Al-Khami, Amir A., Trillo-Tinoco, Jimena, Zarreii, Parisa, Ochoa, Augusto C., Cui, Yan, Del Valle, Luis, Rodriguez, Paulo C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171711/
https://ncbi.nlm.nih.gov/pubmed/25238096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.08.015
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