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Separation of mAbs molecular variants by analytical hydrophobic interaction chromatography HPLC: overview and applications
Hydrophobic interaction chromatography-high performance liquid chromatography (HIC-HPLC) is a powerful analytical method used for the separation of molecular variants of therapeutic proteins. The method has been employed for monitoring various post-translational modifications, including proteolytic...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4171020/ https://ncbi.nlm.nih.gov/pubmed/24751784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.28693 |
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