Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD

Cancer cells display enhanced glycolysis to meet their energetic and biosynthetic demands even under normal oxygen concentrations. Recent studies have revealed that tumor suppressor p53 represses glycolysis under normoxia as a novel mechanism for tumor suppression. As the common microenvironmental s...

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Autores principales: Zhang, Cen, Liu, Juan, Wu, Rui, Liang, Yingjian, Lin, Meihua, Liu, Jia, Chan, Chang S., Hu, Wenwei, Feng, Zhaohui
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170611/
https://ncbi.nlm.nih.gov/pubmed/25114038
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