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Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD

Cancer cells display enhanced glycolysis to meet their energetic and biosynthetic demands even under normal oxygen concentrations. Recent studies have revealed that tumor suppressor p53 represses glycolysis under normoxia as a novel mechanism for tumor suppression. As the common microenvironmental s...

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Detalhes bibliográficos
Main Authors: Zhang, Cen, Liu, Juan, Wu, Rui, Liang, Yingjian, Lin, Meihua, Liu, Jia, Chan, Chang S., Hu, Wenwei, Feng, Zhaohui
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170611/
https://ncbi.nlm.nih.gov/pubmed/25114038
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