Loss of PPM1A expression enhances invasion and the epithelial-to-mesenchymal transition in bladder cancer by activating the TGF-β/Smad signaling pathway

The transforming growth factor-β (TGF-β) signaling pathway is believed to contribute to carcinoma development by increasing cell invasiveness and metastasis and inducing the epithelial-to-mesenchymal transition (EMT). Protein phosphatase PPM1A has been reported to dephosphorylate TGF-β-activated Sma...

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Autors principals: Geng, Jiang, Fan, Jie, Ouyang, Qi, Zhang, Xiaopeng, Zhang, Xiaolong, Yu, Juan, Xu, Zude, Li, Qianyu, Yao, Xudong, Liu, Xiuping, Zheng, Junhua
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170610/
https://ncbi.nlm.nih.gov/pubmed/25026293
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