Novel celastrol derivatives inhibit the growth of hepatocellular carcinoma patient-derived xenografts

The molecular co-chaperone CDC37 is over-expressed in hepatocellular carcinoma (HCC) cells, where it functions with HSP90 to regulate the activity of protein kinases in multiple oncogenic signaling pathways that contribute towards hepatocarcinogenesis. Disruption of these signaling pathways via inhi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wei, Wei, Wu, Song, Wang, Xiaolin, Sun, Chris Kin-Wai, Yang, Xiaoyang, Yan, Xinrui, Chua, Mei-Sze, So, Samuel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2014
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170594/
https://ncbi.nlm.nih.gov/pubmed/25051375
Tagiau: Ychwanegu Tag
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