Imaging of hepatocellular carcinoma patient-derived xenografts using (89)Zr-labeled anti-glypican-3 monoclonal antibody

Imaging probes for early detection of hepatocellular carcinoma (HCC) are highly desired to overcome current diagnostic limitations which lead to poor prognosis. The membrane protein glypican-3 (GPC3) is a potential molecular target for early HCC detection as it is over-expressed in >50% of HCCs,...

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Veröffentlicht in:Biomaterials
Hauptverfasser: Yang, Xiaoyang, Liu, Hongguang, Sun, Chris K., Natarajan, Arutselvan, Hu, Xiang, Wang, Xiaolin, Allegretta, Mark, Guttmann, Ronald D., Gambhir, Sanjiv S., Chua, Mei-Sze, Cheng, Zhen, So, Samuel K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363564/
https://ncbi.nlm.nih.gov/pubmed/24836949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.04.089
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