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WT1 Interacts with MAD2 and Regulates Mitotic Checkpoint Function

Tumor suppressors safeguard the fidelity of the mitotic checkpoint by transcriptional regulation of genes that encode components of the mitotic checkpoint complex (MCC). Here we report a new role for the tumor suppressor and transcription factor, WT1, in the mitotic checkpoint. We show that WT1 regu...

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Autors principals: Shandilya, Jayasha, Toska, Eneda, Richard, Derek J, Medler, Kathryn F, Roberts, Stefan GE
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170573/
https://ncbi.nlm.nih.gov/pubmed/25232865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5903
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