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Structural analyses of Ca(2+)/CaM interaction with Na(V) channel C-termini reveal mechanisms of calcium-dependent regulation

Ca(2+) regulates voltage-gated Na(+) (Na(V)) channels and perturbed Ca(2+) regulation of Na(V) function is associated with epilepsy syndromes, autism, and cardiac arrhythmias. Understanding the disease mechanisms, however, has been hindered by a lack of structural information and competing models fo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wang, Chaojian, Chung, Ben C., Yan, Haidun, Wang, Hong-Gang, Lee, Seok-Yong, Pitt, Geoffrey S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170523/
https://ncbi.nlm.nih.gov/pubmed/25232683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5896
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