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Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin

Voltage-gated Na(+) (Na(V)) channels initiate neuronal action potentials. Na(V) channels are composed of a transmembrane domain responsible for voltage-dependent Na(+) conduction and a cytosolic C-terminal domain (CTD) that regulates channel function through interactions with many auxiliary proteins...

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Detalhes bibliográficos
Main Authors: Wang, Chaojian, Chung, Ben C., Yan, Haidun, Lee, Seok-Yong, Pitt, Geoffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610540/
https://ncbi.nlm.nih.gov/pubmed/22705208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.05.001
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