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Identification of Novel Interaction Sites that Determine Specificity between Fibroblast Growth Factor Homologous Factors and Voltage-gated Sodium Channels

Fibroblast growth factor homologous factors (FHFs, FGF11–14) bind to the C termini (CTs) of specific voltage-gated sodium channels (VGSC) and thereby regulate their function. The effect of an individual FHF on a specific VGSC varies greatly depending upon the individual FHF isoform. How individual F...

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Detalhes bibliográficos
Main Authors: Wang, Chaojian, Wang, Chuan, Hoch, Ethan G., Pitt, Geoffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129206/
https://ncbi.nlm.nih.gov/pubmed/21566136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245803
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