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Nucleus-targeted Dmp1 transgene fails to rescue dental defects in Dmp1 null mice
Dentin matrix protein 1 (DMP1) is essential to odontogenesis. Its mutations in human subjects lead to dental problems such as dental deformities, hypomineralization and periodontal impairment. Primarily, DMP1 is considered as an extracellular matrix protein that promotes hydroxyapatite formation and...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4170153/ https://ncbi.nlm.nih.gov/pubmed/25105818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijos.2014.44 |
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