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Transgenic expression of dentin phosphoprotein (DPP) partially rescued the dentin defects of DSPP-null mice
Mutations in the dentin sialophosphoprotein (DSPP) gene cause dentinogenesis imperfecta. After synthesis, DSPP is proteolytically processed into NH(2)- and COOH-terminal fragments. The NH(2)-terminal fragment of DSPP is highly glycosylated but not phosphorylated, whereas the COOH-terminal fragment (...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5908185/ https://ncbi.nlm.nih.gov/pubmed/29672573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195854 |
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