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Astacin Proteases Cleave Dentin Sialophosphoprotein (Dspp) to Generate Dentin Phosphoprotein (Dpp)

Dentin sialophosphoprotein (Dspp) is critical for proper dentin biomineralization because genetic defects in DSPP cause dentin dysplasia type II and dentinogenesis imperfecta types II and III. Dspp is processed by proteases into smaller subunits; the initial cleavage releases dentin phosphoprotein (...

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Detalhes bibliográficos
Main Authors: Tsuchiya, Shuhei, Simmer, James P, Hu, Jan C-C, Richardson, Amelia S, Yamakoshi, Fumiko, Yamakoshi, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179315/
https://ncbi.nlm.nih.gov/pubmed/20687161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.202
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