Inhibition of TYK2 and JAK1 Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis by Inhibiting IL-22 and the IL-23/IL-17 axis

Psoriasis is a chronic autoimmune disease affecting the skin and characterized by aberrant keratinocyte proliferation and function. Immune cells infiltrate the skin and release proinflammatory cytokines that play important roles in psoriasis. The Th17 network, including IL-23 and IL-22, has recently...

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書誌詳細
主要な著者: Works, Melissa G., Yin, Fangfang, Yin, Catherine C., Yiu, Ying, Shew, Kenneth, Tran, Thanh-Thuy, Dunlap, Nahoko, Lam, Jennifer, Mitchell, Tim, Reader, John, Stein, Paul L., D’Andrea, Annalisa
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170002/
https://ncbi.nlm.nih.gov/pubmed/25156366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400205
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