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Reprogramming the specificity of sortase enzymes
Staphylococcus aureus sortase A catalyzes the transpeptidation of an LPXTG peptide acceptor and a glycine-linked peptide donor and has proven to be a powerful tool for site-specific protein modification. The substrate specificity of sortase A is stringent, limiting its broader utility. Here we repor...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169943/ https://ncbi.nlm.nih.gov/pubmed/25187567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411179111 |
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