Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R

Among the single-nucleotide polymorphisms (SNPs) previously reported to be associated with body mass index (BMI) and obesity, we focus on a common risk variant rs7566605 upstream of the insulin-induced gene 2 (INSIG2) gene and a rare protective variant rs2229616 on the melanocortin-4 receptor (MC4R)...

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Bibliographische Detailangaben
Hauptverfasser: Malzahn, Dörthe, Müller-Nurasyid, Martina, Heid, Iris M, Wichmann, H-Erich, Bickeböller, Heike
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169541/
https://ncbi.nlm.nih.gov/pubmed/24518831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.3
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