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Multi-Level Kinetic Model of mRNA Delivery via Transfection of Lipoplexes
Recent work on the use of mRNA lipoplexes for gene delivery demonstrates the need for a mathematical model that simulates and predicts kinetics and transfection efficiency. The small copy numbers involved make it necessary to use stochastic models and include statistical analysis of the variation ob...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169511/ https://ncbi.nlm.nih.gov/pubmed/25237886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107148 |
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