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Multi-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection

Single-cell time-lapse studies have advanced the quantitative understanding of cellular pathways and their inherent cell-to-cell variability. However, parameters retrieved from individual experiments are model dependent and their estimation is limited, if based on solely one kind of experiment. Henc...

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Bibliographic Details
Published in:NPJ Syst Biol Appl
Main Authors: Fröhlich, Fabian, Reiser, Anita, Fink, Laura, Woschée, Daniel, Ligon, Thomas, Theis, Fabian Joachim, Rädler, Joachim Oskar, Hasenauer, Jan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288153/
https://ncbi.nlm.nih.gov/pubmed/30564456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-018-0079-7
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