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MHC Class II Restricted Innate-Like Double Negative T Cells Contribute to Optimal Primary and Secondary Immunity to Leishmania major

Although it is generally believed that CD4(+) T cells play important roles in anti-Leishmania immunity, some studies suggest that they may be dispensable, and that MHC II-restricted CD3(+)CD4(−)CD8(−) (double negative, DN) T cells may be more important in regulating primary anti-Leishmania immunity....

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Bibliografiske detaljer
Main Authors: Mou, Zhirong, Liu, Dong, Okwor, Ifeoma, Jia, Ping, Orihara, Kanami, Uzonna, Jude Ezeh
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169504/
https://ncbi.nlm.nih.gov/pubmed/25233487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004396
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