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CD8(+) T cells Are Preferentially Activated during Primary Low Dose Leishmania major Infection but Are Completely Dispensable during Secondary Anti-Leishmania Immunity

We previously showed that CD8(+) T cells are required for optimal primary immunity to low dose Leishmania major infection. However, it is not known whether immunity induced by low dose infection is durable and whether CD8(+) T cells contribute to secondary immunity following recovery from low dose i...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Okwor, Ifeoma B., Jia, Ping, Mou, Zhirong, Onyilagha, Chukwunonso, Uzonna, Jude E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238992/
https://ncbi.nlm.nih.gov/pubmed/25412267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003300
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