Functional Fluorescent Protein Insertions in Herpes Simplex Virus gB Report on gB Conformation before and after Execution of Membrane Fusion

Entry of herpes simplex virus (HSV) into a target cell requires complex interactions and conformational changes by viral glycoproteins gD, gH/gL, and gB. During viral entry, gB transitions from a prefusion to a postfusion conformation, driving fusion of the viral envelope with the host cell membrane...

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Bibliographische Detailangaben
Hauptverfasser: Gallagher, John R., Atanasiu, Doina, Saw, Wan Ting, Paradisgarten, Matthew J., Whitbeck, J. Charles, Eisenberg, Roselyn J., Cohen, Gary H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169481/
https://ncbi.nlm.nih.gov/pubmed/25233449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004373
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