Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion

Herpes simplex virus entry into cells requires four glycoproteins, gB, gD, gH, and gL. Binding of gD to one of its receptors triggers steps requiring the core fusion proteins, gB and the gH/gL heterodimer. There is evidence that gH/gL initiates hemifusion of cells, but whether this complex interacts...

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Bibliographische Detailangaben
Hauptverfasser: Atanasiu, Doina, Whitbeck, J. Charles, Cairns, Tina M., Reilly, Brigid, Cohen, Gary H., Eisenberg, Roselyn J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141843/
https://ncbi.nlm.nih.gov/pubmed/18003913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707452104
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