Sortase A Induces Th17-Mediated and Antibody-Independent Immunity to Heterologous Serotypes of Group A Streptococci

Group A streptococci (GAS) are associated with a variety of mucosal and invasive human infections. Recurrent infections by highly heterologous serotypes indicate that cross-serotype immunity is critical for prevention of GAS infections; however, mechanisms underlying serotype-independent protection...

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Detalhes bibliográficos
Main Authors: Fan, Xin, Wang, Xiaoshuang, Li, Ning, Cui, Honglian, Hou, Baidong, Gao, Bin, Cleary, Paul Patrick, Wang, Beinan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169422/
https://ncbi.nlm.nih.gov/pubmed/25232948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107638
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