Th17 cells mediate clade specific, serotype-independent mucosal immunity

The interleukin-17 (IL-17) family of cytokines phylogenetically pre-dates the evolution of T cells in jawed vertebrates, suggesting that the ontogeny of the Th17 cell lineage must have arisen to confer an evolutionary advantage to the host over innate sources of IL-17. Using a model of mucosal immun...

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Bibliographic Details
Main Authors: Chen, Kong, McAleer, Jeremy P., Lin, Yuan, Paterson, David L., Zheng, Mingquan, Alcorn, John F., Weaver, Casey T., Kolls, Jay K.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406408/
https://ncbi.nlm.nih.gov/pubmed/22195749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.10.018
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