Biglycan deficiency: increased aortic aneurysm formation and lack of atheroprotection

BACKGROUND: Proteoglycans of the arterial wall play a critical role in vascular integrity and the development of atherosclerosis owing to their ability to organize extracellular matrix molecules and to bind and retain atherogenic apolipoprotein (apo)-B containing lipoproteins. Prior studies have sug...

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Autori principali: Tang, Tao, Thompson, Joel C., Wilson, Patricia G., Yoder, Meghan H., Müeller, Julia, Fischer, Jens W., Jon Williams, Kevin, Tannock, Lisa R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169288/
https://ncbi.nlm.nih.gov/pubmed/25093698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.07.014
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