Renal Accumulation of Biglycan and Lipid Retention Accelerates Diabetic Nephropathy

Hyperlipidemia worsens diabetic nephropathy, although the mechanism by which renal lipids accumulate is unknown. We previously demonstrated that renal proteoglycans have high low-density lipoprotein (LDL) binding affinity, suggesting that proteoglycan-mediated LDL retention may contribute to renal l...

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Bibliografiske detaljer
Main Authors: Thompson, Joel, Wilson, Patricia, Brandewie, Katie, Taneja, Deepa, Schaefer, Liliana, Mitchell, Bonnie, Tannock, Lisa R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157166/
https://ncbi.nlm.nih.gov/pubmed/21723246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.016
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